Tapentadol is an analgesic approved by the FDA. It helps to manage chronic and severe pain effectively when the first line of pain medications do not provide effective benefits. Tapentadol common brands are Aspadol and Nucynta.

Tapentadol kicks in within 30 minutes and the efficacy lasts for 4 to 6 hours. The Tapentadol half-life duration is 4 hours and stays in the system for up to 20 to 22 hours. However, factors like the dosage, metabolism, age, etc of the consumers might alter the duration.

For more detailed description on how long does Tapentadol stays in the system read the blog written by Dr. Kelly Walker, provided below, at HealthNaturo.